College of Health and Human Performance

UFHHP Spaces: Laboratory of Basic and Clinical Muscle Biology

Take a virtual tour of HHP’s lab run by Leonardo Ferreira, Ph.D., associate professor in the Department of Applied Physiology and Kinesiology

January 20, 2021

Laboratory of Basic and Clinical Muscle BiologySnap Content

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Dr. Ferreira and his team of researchers are focused on understanding how diseases cause muscle weakness, especially through loss of contractile function. Their primary interest is in heart failure, but they also collaborate with other research groups on campus to study weakness in cancer, sepsis and patients undergoing surgery. 

The lab, located on the northside of the Florida Gym, has been in place since 2013 and includes senior biological scientists, post-doctoral researchers, graduate and undergraduate students. About 6-8 people work in the lab at any given time.

The research goal is to identify therapeutic targets to counteract the loss of muscle function in using pharmacological interventions and exercise. They investigate basic mechanisms at cellular and molecular level and use a translational approach with studies in pre-clinical models and patients.

Recent articles from the lab have appeared in the Journal of Molecular and Cellular Cardiology, American Journal of Respiratory and Critical Care Medicine, Journal of Physiology, and American Journal of Physiology – Lung Cellular and Molecular Physiology.

Funding is received from the NIH, American Heart Association and partnerships with pharmaceutical companies to test novel therapies for muscle weakness.


Continue the tour – Visit the UFHHP Ethanol, Drug, and Gambling Experimental Lab >

UFHHP Spaces is a pilot project. We'd love your feedback and to hear what spaces you'd like to see next. Take our survey >


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